منابع مشابه
The Role of Allium saralicum Extract on Prevention of Acetaminophen-Induced Hepatic Failure: an Experimental Study
Background and objectives: Acetaminophen (APAP) is a common analgesic medicine whose overdose leads to severe hepatic dysfunction. Due to the known antioxidant properties of Alliumspecies, the present study aimed to evaluate the protective effects of Allium saralicum plant on APAP induced liver toxicity. Methods: The hydro-alcoholic e...
متن کاملA new experimental model for acute hepatic failure in rats.
PURPOSE To develop a reliable surgical model of acute hepatic failure and hyperammonemia in rats that avoids porto-systemic shunt and bile duct ligation, applicable to hepatic encephalopathy research. METHODS The pedicles of right lateral and caudate lobes were exposed and clamped. One hour later, the animal was reopened, clamps were released and anterior subtotal hepatectomy (resection of me...
متن کاملAn Experimental Animal Model of Fulminant Hepatic Failure in Pigs
The objective of this study was to develop an experimental animal model of fulminant hepatic failure to test the efficacy of the bioartificial liver system. The portal vein and the hepatic artery were clamped intermittently and then the hepatic artery was ligated (ligation group, n=5). Pigs whose hepatic arteries were not ligated after clamping were assigned to the non-ligation group (n=5). The...
متن کاملZinc content in liver of experimental fulminant hepatic failure rat.
A rat model of fulminant hepatic failure induced by D-galactosamine (Gal) was given glucagon and insulin. The amount of Zn contained in its liver was measured and investigated for use as an index to the progress of hepatic failure and to the hepatic regeneration. The results showed that the Zn content in the rat's liver had been rapidly reduced to the lowest value 48 hours after Gal was given b...
متن کاملGlyphosate Poisoning with Acute Fulminant Hepatic Failure
Background: Glyphosate containing herbicides are widely used the world over. They are marketed as nontoxic to humans, but numerous studies have showed that these glyphosate-based herbicides (GlySH) can cause multiorgan damage.1 Recent reports of animal studies on rats have raised a doubt of liver damage after long term exposure to GlySH. Case Presentation: a young male had chronic exposure to G...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: BMJ
سال: 1955
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.4911.459